For any drug developer or service provider, cell line development is one of the most challenging phases, especially when subsequent GMP compliance is required.

To boost and support successful commercial introduction of biological drugs to the market, Celonic has engineered CHOvolution™, a cell line development platform for the generation of high-level expression cell lines for new biological entities (NBEs) and biosimilar products.

This is an innovative integrated cell line kit that can be used for a broad range of applications, ranging from non‑GMP R&D testing to GMP development and commercial market supply, with a support system to help throughout every step of development.

CHOvolution™ Key features:

  • Powered by Celonic's proprietary SEFEX Technology
  • Cell line based on CHO-K1 (non genetically modified CHO)
  • Cell line adapted to serum-free EMA and FDA compliant media
  • Simplified licensing model (e.g. no royalties from sales)High productivity (>7 g/l for mABs)
  • High scale-up stability (over the 120 generation cycles and easily scalable from shake flask to >1000L)
  • GMP compliant, from R&D to market manufacturing
  • Cell line in several clinical trials in EU/US and Asia
  • Tailored workshops and hands-on training to develop the product
  • Technical and scientific support on the CHOvolution™ platform


We look forward to helping you with your projects. Mr Stavros Theocharidis is available to answer any enquiries about cell lines and cell culture, as well as discuss with you the new opportunities we can develop for you as your provider and partner. 

E-mail: chovolution@celonic.ch

Phone: +41 61 202 94 25