How CHOvolution™ works

Cell Line development process Overview

CHOvolution™ is based on a CHO-K1 host cell line, a set of high level expression vectors and extensively refined protocols for the best screening and selection processes.

The development strategy is based on a regulatory-compliant method for cloning, transfection, selection and single-cell cloning, using our proprietary, fully tested, non genetically modified CHO-K1 host cell line adapted to chemically defined serum-free medium. This powerful platform can be used throughout the entire product development process from laboratory cultures (R&D) to production scale (cGMP).

Next steps

Celonic as a premier CDMO can take you further and provides:

  • Robust, GMP-compliant and efficient process and methods development
  • GMP biomanufacturing for clinical and Commercial market purposes