CHOvolution™ - High scalability in each step

Celonic has worked extensively on the development of expression vectors, cell lines and media, resulting in its proprietary serumfree expression platform technology, SEFEX (SErum Free EXpression) for the development of high-yield production cell lines without using gene amplification.

The result is a highly robust and scalable platform where growth behavior in the haking flask is almost identical to a 1000 L fed batch. The high genetic stability and robustness against mechanical stress allows for process development and scale-up in a straightforward approach, saving both development time and Money.