Bio-development services
Cell Expression Platforms
Celonic offers two standardized cell line development platforms which can be adapted according to the specific needs of our customers.
Innovative industry-leading cell expression platforms
CHOvolution® is the optimal platform for the high-titer bioproduction of monoclonal antibodies in a fed-batch process, saving time and costs. In case you are dealing with a defucosylated antibody, complex molecule and/or glycosylated protein, our human GEX® platform is the solution.
- SIMPLIFIED LICENSING MODEL
(e.g. no royalties from sales) - PRODUCT DERIVED FROM CHO AND GEX PLATFORMS ARE IN SEVERAL CLINICAL TRIALS IN EU, USA & ASIA
- HIGH SCALE-UP STABILITY
- CELL LINES SUSPENSION-ADAPTED TO SERUM-FREE EMA- AND FDA-COMPLIANT MEDIA
- COMPLIANCE TO cGMP GUIDELINES
- WELL CHARACTERIZED PARENTAL CELL LINE CULTURED UNDER DOCUMENTED ANIMAL-FREE CONDITIONS
CHOvolution®
- Powered by Celonic’s proprietary SEFEX® technology platform
- High productivity (capable of delivering up to 8 g/L for mABs)
- Rapid cell line development: save up to 4 months
- Real Freedom from royalties and binding terms
For more information please contact:
E: chovolution@celonic.com
GEX®
- Human cells which can be used to specifically tailor glycosylation
- Ideal for perfusion cell culture
- Optimized for complex biopharmaceutical products
- Stable product quality during entire cell culture process
For more information please contact:
E: gex@celonic.com
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