CHOvolution™ is a CHO-K1 based expression platform that can be used for a broad range of applications, ranging from non‑GMP R&D testing to GMP development and commercial market supply, with a support system to help throughout every step of development.
Besides offering cell line development services, Celonic is selling/outlicensing the system to other service providers or drug developers.
The CHOvolution™ technology is proven for:
Its key features are :
The GEX® technology allows the optimization of glycosylation to improve activity and/or other properties like bioavailability, stability, and/or immunogenicity for better clinical performance.
It is based on human cell lines which are optimized for both product quality optimization and fast, high reproducible and high yield glycoprotein manufacturing.
An established fermentation process provides homogenous and stable glycosylation patterns as well as general consistant batch-to-batch product quality.
The GEX® technology is proven for:
GEX® has regulatory approval by FDA, EMA and German regulatory authorities (PEI, BfArM) for manufacturing of biopharmaceuticals.
Mr. Stavros Theocharidis is available to answer any enquiries about CHOvolution™, cell lines and cell culture, as well as discuss new opportunities with you. We can develop for you as your provider and partner.
Phone: +41 61 202 94 25