Diagnostics

Immunodiagnostics

Celonic's product line of diagnostic reagent kits is based on flow cytometry procedures for the fast, accurate and precise measurement of various cell functions. Our focus is the functional characterisation of the cellular immune response. The kits are designed as ready-to-use reagent kits for routine clinical use.

Its key features are:

Kits

We offer a range of flow cytometry-based assays for analyzing the functional activity of neutrophilic granulocytes, monocytes, basophilic granulocytes, natural killer cells and thrombocytes:

Thrombocytest

A clinical diagnostic for the flow cytometric quantitation of platelet associated immunoglobulin. The reagent kit contains various polyclonal antibodies labeled with the fluorescence dye, phycoerythrin (PE) as follows: antibodies against total human immunoglobulins, as well as human IgA, IgM and IgG, and polyclonal antibodies against rabbit immunoglobulin as a negative control. The test kit also contains a fluorescein isothiocyanate (FITC) conjugated monoclonal antibody, which recognizes a platelet-specific antigen, and further necessary reagents.

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Basotest

A clinical diagnostic for the flow cytometric determination of basophil degranulation in heparinized whole blood. The reagent kit contains the chemotactic peptide, N-formyl-Met-Leu-Phe (fMLP) as positive control, important allergens, a two-color antibody reagent for assessing the activation of human basophilic granulocytes and necessary reagents.

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NKtest

A clinical diagnostic for the quantification of the cytotoxic activity of human natural killer cells. The reagent kit contains cryopreserved pre-stained K562 target cells, complete medium and a DNA- staining reagent.

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Phagoburst

A clinical diagnostic for the quantitative flow cytometric determination of leukocyte oxidative burst in heparinized whole blood. The reagent kit contains unlabeled opsonized bacteria (E.coli), phorbol 12-myristate 13-acetate (PMA) and the chemotactic peptide, N-formyl-Met-Leu-Phe (fMLP), as stimulants, dihydrorhodamine (DHR) 123 as a fluorogenic substrate and necessary reagents.

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Phagotest

A clinical diagnostic for the quantitative flow cytometric determination of leukocyte phagocytosis in heparinized whole blood. The reagent kit contains fluorescein (FITC)-labelled opsonized E.coli bacteria and necessary reagents.

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Migratest

A clinical diagnostic for the flow cytometric determination of the chemotactic function of granulocytes. The reagent kit contains multi-well plates and pre-coated cell culture inserts, the chemotactic peptide, N-formyl-Met-Leu-Phe (fMLP), an antibody reagent, counting beads and necessary reagents.

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